· Gary O'Keeffe · Life Sciences
How We Cut a Lab's AWS Bill by 45%
A midsize life sciences lab running a LIMS on AWS. We found the waste and worked with them to cut the bill by 45%.
Insights
Resources
Practical notes on LIMS migrations, lab data engineering, and production machine learning.
Topics
· Kevin Bolger · AI & DataLinking Instrument Files to LIMS Records
The raw file exists. The LIMS record exists. Connecting them is the work that makes both useful.
· Shannon Alliance · Life SciencesA LIMS Migration Blueprint: Transitioning a High-Throughput Genomics Lab from Legacy LabVantage to Cloud-Native QBench
How a high-throughput genomics lab moved from a self-hosted LabVantage and Oracle stack to QBench with zero downtime, five-figure annual savings, and CAP/CLIA-validated reporting.
· Gary O'Keeffe · AI & DataWarehouse, Lakehouse, or Search Index?
Three architectures for making lab data queryable. Which one fits depends on what questions you're asking.
· Shannon Alliance · Life SciencesWhy Querying the Database Directly is the Best Way to Do Data Engineering on On-Prem LabVantage LIMS
Query an on-prem LabVantage database with a read-only Python wrapper instead of Java extensions, so pipelines stay portable across Oracle and SQL Server.
· Gary O'Keeffe · AI & DataConnecting Gemini to Your Lab Data
Gemini in Workspace and Gemini Enterprise are different products with different capabilities. Here's what you can actually connect.
· Shannon Alliance · Life SciencesContinuous CAP/CLIA Validation: Automating Integration Testing for Self-Hosted to SaaS LIMS Migrations
How a genomics lab stays CAP/CLIA validated across ad-hoc QBench releases with a full API regression suite and an audit PDF before each production update.
· Kevin Bolger · AI & DataMicrosoft 365 Copilot and Lab Data
Copilot already sees your SharePoint. Getting it to see your LIMS and instrument data is a different problem.
· Kevin Bolger · AI & DataHow to Connect ChatGPT Enterprise to Internal Lab Data
ChatGPT Enterprise supports custom MCP apps. Here's how to connect it to lab data with proper controls.
· Shannon Alliance · Life SciencesProductizing LIMS Data Transfer Agreements: How Regulated Labs Stop Burning Engineering Hours on Custom Exports
Treat client data transfer agreements as a priced menu, so custom LIMS exports stop consuming unpaid engineering time.
· Gary O'Keeffe · AI & DataHow to Connect Claude Enterprise to Your Internal Lab Data
Claude runs in Anthropic's cloud. Your LIMS and file shares don't. Here are the secure options that exist today.
· Shannon Alliance · AI & DataIs Your Lab Data AI-Ready?
A practical checklist for life science teams. When AI projects stall, the data is often the reason, not the model.
· Gary O'Keeffe · AI & DataWhere Dark Data Hides in a Lab
Dark data tends to hide in the same few places. Here's where to look and how to find it in a week.
· Shannon Alliance · Life SciencesFrom Dark Data to Daily Insights: How BigQuery Transformed a Digital Pathology Lab
A digital pathology partner needed a regular count of samples stained with a given assay, and which analysis was paired with it. The answer lived in three systems.
· Gary O'Keeffe · Data EngineeringLean Agent Development: Transform Ideas into MVMs into MVPs
The 5 D's of lean agent development, so you only break ground on an idea once you know the bet is worth making.
· Gary O'Keeffe · Life SciencesR versus Python for Bioinformatics Research
When a Bioinformatics researcher starts a new project, one of the first significant Computer Science decisions they need to make is picking a programming language.The R and Python programming language
· Kevin Bolger · MLOpsMastering ML Ops: A Blueprint for Success
Mastering ML Ops: A Blueprint for Success